Glia

Hereditary spastic paraplegia (HSP) gene 11 (Spg11) attenuates lipid accumulation in myeloid cells and neuroinflammation in the midbrain without affecting α-synuclein pathology

Loss of Spg11 drives microglial activation and myeloid lipid accumulation independent of α-synuclein pathology.

Integrated Cross-Disease Atlas of Human And Mouse Astrocytes Reveals Heterogeneity and Conservation of Astrocyte Subtypes in Neurodegeneration

Atlas effort of astrocytes reveals disease association and specieices conservation